Depression and Lithium

Introduction

Lithium has been used medicinally since ancient times and is a prominent therapeutic option in psychiatry for conditions such as schizophrenia, bipolar disorder, and psychotic disorders.

Low Dose Lithium

Low dose lithium, typically administered as lithium orotate at doses ranging from 1-30mg/day, is gaining popularity as a safe and effective intervention for various conditions.

Lithium for Depression

Depression is a heterogeneous disorder with varying symptoms. While lithium is not typically listed as a treatment for depression, it can be beneficial for patients with symptoms of irritability and agitation.

Irritability and Agitation

Chronic irritability has been identified as a core feature of many psychiatric disorders and is associated with longer and more intensive treatments. Low dose lithium can alleviate irritability and aggression and is highly protective against suicidal thoughts and behaviors.

Conclusion

Low dose lithium has a place in the treatment of depression with features of irritability and agitation. It can contribute significantly to patients’ therapeutic progress and increase their chances of lasting recovery.