Description
Levitra is a medication that contains Vardenafil HCl, available in doses ranging from 5 mg to 60 mg. Vardenafil HCl is a solid substance with a molecular weight of 579.1 g/mol and a solubility of 0.11 mg/mL in water. The tablets are orange, round, and film-coated with ‘BAYER’ cross debossed on one side and the respective dose on the other.
Pharmacology of Levitra 5 mg Pills
Levitra works by relaxing the smooth muscles of the cavernous body and arterioles in the penis, increasing blood flow and causing an erection. Sexual stimulation releases Nitric oxide (NO), which activates the enzyme Guanylate Cyclase, leading to an increase in cyclic guanosine monophosphate (cGMP) in the cavernous bodies. The level of cGMP is regulated by phosphodiesterases (PDE), including PDE5, which Levitra inhibits. Other PDE5 inhibitors include Sildenafil, Tadalafil, and Avanafil.
Pharmacodynamics of Levitra 5 mg
Levitra 5 mg is rapidly absorbed and reaches peak concentration after 60 minutes. The recommended dose ranges from 5 mg to 20 mg, with a total clearance time of 4-5 hours. Food intake does not affect the pharmacokinetic parameters of Levitra.
Other Available Variants of Levitra 5 mg
BigpharmaUSA supplies other variants of Levitra besides the 5 mg variant.
Dosage and Proper Administration
The recommended dose is one tablet of Levitra 10 mg taken 30-60 minutes before sexual activity. The dose may be increased to one tablet of Levitra 20 mg or reduced to 5 mg per day, with a maximum recommended dose of 20 mg once daily. Levitra is not suitable for children and teens below 18 years or elders above 65 years. Patients with hepatic or renal impairment should consult their doctor for dosage adjustments.
Other Drug’s Effects on Levitra 5 mg
Levitra should not be taken with drugs that interact with it, such as erythromycin, clarithromycin, ketoconazole, itraconazole, indinavir, ritonavir, atazanavir, grapefruit juice, alcohol, and nitrates. It can also cause chest pain and exaggerate blood pressure-lowering effects.
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