Buy Hydrocodone Online: A Comprehensive Guide
Hydrocodone medicine is FDA approved to manage severe pain. People also buy Hydrocodone online which can be indicated to cure cough in adults above the age of 18 years. Online Hydrocodone is available with a valid prescription from an authorized doctor. Let’s further discuss every related aspect of Hydrocodone usage, dosage, online accessibility, etc. in detail.
How and Where to Buy Hydrocodone Online
If you are willing to buy Hydrocodone online or order Hydrocodone from Big pharma USA, follow these steps:
- Visit the ‘Big pharma USA’ website.
- Click on the ‘Shop’ button.
- After that search for the ‘Pain Relief’ category.
- Followed by clicking on the ‘Buy Hydrocodone Online’ option.
- From the ‘Buy Hydrocodone Online’ page, choose the desired dose and quantity.
- Finally, click on the ‘Add to cart’ button to place an order.
About Hydrocodone
Hydrocodone is a medicine that is classified under Schedule II controlled substance drugs. That is why Hydrocodone without a prescription is no more available. Even to order Hydrocodone online, you have to produce a valid prescription at the time of buy.
The mixture of Hydrocodone and Acetaminophen is supplied under the trade name Vicodin and Lortab. These semi-synthetic opioid medicines are usually used when other opioid medicines are unable to cure chronic muscle spasms and severe body pain.
Contraindications Conditions
Usage of Hydrocodone under certain medical conditions is prohibited. You must inform your doctor if you have any of these health conditions:
- Problems while breathing, sleep apnea
- Weaker pulse or a slowed heart rate
- Irritation while urinating
- Confusion
- Tremors and shaking
- Severe drowsiness
- Feeling lightheaded
- Nausea, vomiting, and diarrhea
- Low cortisol levels
- High levels of serotonin in the system
- Hypersensitivity to Hydrocodone
- Bronchial asthma
Hydrocodone’s Mechanism
Hydrocodone is an opioid receptor agonist that produces analgesic effects by activating mu-opioid receptors. It tends to activate delta-opioid receptors and kappa-opioid receptors present in an individual’s brain. Opioid receptors are primarily found within the central nervous system, in the enteric plexus, interstitial cells of Cajal, and immune cells present in the gastrointestinal tract.
Pharmacokinetics of Hydrocodone
Hydrocodone like all other medicines is metabolized in the liver. The cytochrome P450 enzymes CYP2D6 and CYP3A4 converts Hydrocodone to its active metabolite, hydromorphone. Clinical studies have observed that pain relief is correlated with plasma concentrations of hydromorphone rather than hydrocodone.
Hydrocodone IR (Immediate Release) and ER (Extended Release) reach peak concentration within 1 hour and 5-30 hours, respectively. The half-life elimination of Hydrocodone IR and ER is approximately 4 hours and 7-12 hours, respectively. Hydrocodone and its metabolites are ejected from the system via the urine.
Dosage and Usage
Hydrocodone medicine is available in various formulations depending on the manufacturer. Currently, Hydrocodone is supplied in the form of:
- Oral tablets
- Capsules
- Oral solutions
Tablets and capsules are not meant to be crushed, chewed, or dissolved while ingesting the dose. This may lead to uncontrolled rapid medication delivery in the system and eventually, an overdose may cause.
This medication is available in different variants for the convenience of its users. In the present day, Hydrocodone is supplied by Bigpharma USA in the following variants:
- Geriatric dosage:
1-2 tablets of Hydrocodone 5/325 mg are prescribed to be taken every 4–6 hours. The maximum dosage should not exceed 8 tablets in a day.
- Adult dosage:
1 tablet of 10/325 mg of Hydrocodone is the typical dosage for adult usage. The maximum dosage to
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