The Provigil 200 mg medication is not a cure for sleep disorders, but it can help improve excessive sleepiness when used in conjunction with proper treatment procedures and therapy. Each Provigil 200 mg tablet contains the amphetamine salt of Modafinil, which is similar to the armodafinil drug (Nuvigil). Provigil is also available in 100 mg pills.
Working Duration and Half-life
Modafinil promotes wakefulness by stimulating the brain and increasing the amount of dopamine, a chemical neurotransmitter present in the brain. The effects of Provigil typically kick in within 30 to 60 minutes after administration on an empty stomach, with peak blood concentration achieved around 1 to 2 hours post-administration. Provigil’s half-life ranges from 10 to 12 hours for most patients, but it may last up to 15 hours in some individuals.
How to Use Provigil 200 mg
For the treatment of narcolepsy, Provigil medication should be taken by mouth with or without food once daily in the morning or as directed by a doctor. The total daily dose of Provigil 200 mg may be divided into a smaller morning dose and a noon dose. To treat obstructive sleep apnea, take Provigil once daily in the morning. For shift work sleep disorder, take Provigil orally with or without food once daily, 1 hour before starting the work shift. Take this medication regularly to get the most benefit and avoid sudden discontinuation.
The general recommended dose for an individual is 200 mg of Provigil once daily, not exceeding the 400 mg limit. It should be taken one hour prior to work by those dealing with shift work disorder.
Avoid using Provigil if you have heart problems, high blood pressure, liver or kidney problems, or mental disorders such as depression, mania, and psychosis. Individuals with a personal or family history of substance use disorder should also use Provigil carefully.
Provigil treatment should be carefully monitored if taken with certain drugs, such as cyclosporine, hormonal contraceptives, warfarin, diazepam, propranolol, imipramine, mephenytoin, carbamazepine, phenobarbital, rifampin, ketoconazole, itraconazole, and methylphenidate. Alcohol and opioid painkillers, sedatives, and sleeping pills should also be avoided while taking Provigil.