Interactions between Codeine / Guaifenesin / Pseudoephedrine and Percocet 5/325.

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Interactions between Your Drugs

When taking narcotic pain or cough medications along with other drugs that also cause central nervous system depression, it can result in serious side effects such as respiratory distress, coma, and even death. It’s important to consult your doctor if you have any concerns or questions. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It’s crucial not to drink alcohol or self-medicate with these medications without your doctor’s approval, and not to exceed the doses or frequency and duration of use prescribed by your doctor. Since these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination, it’s best to avoid driving or operating hazardous machinery until you know how they affect you. Make sure to inform your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and Food Interactions

While receiving treatment with oxyCODONE, avoid using alcohol or medications that contain alcohol. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. You may also want to limit the consumption of grapefruit and grapefruit juice, which can significantly increase the blood levels of oxycodone in some people. Consult your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Do not use more than the recommended dose of oxyCODONE and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Make sure to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

Therapeutic Duplication Warnings

No warnings were found for the selected drugs. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.

– Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.

– Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.

– Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

– Unknown: No interaction information available.

Further Information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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