In What Ways Does Ozempic Assist in Managing PCOS?

Polycystic Ovary Syndrome (PCOS) and Insulin Resistance

Polycystic ovary syndrome (PCOS) is a condition that affects the endocrine system, characterized by reduced fertility, elevated androgens, multiple cysts on the ovaries, and insulin resistance. Insulin resistance is a major factor in PCOS and can lead to type 2 diabetes. Metformin has been used as a treatment for PCOS for years, but there are other options available.

What is Ozempic?

Ozempic is a GLP-1 receptor agonist that is typically used in patients with type 2 diabetes who cannot control their condition with diet and exercise. It is sometimes taken as a weight loss drug by people who do not have diabetes. Ozempic can be an alternative to metformin for people who have difficulty tolerating the drug or if metformin is not working well.

How Does PCOS Relate to Insulin Resistance?

Insulin resistance is a common factor in PCOS, even in patients who are not overweight or obese. Treating insulin resistance can help with weight loss, fertility, and protecting the heart.

How is Insulin Resistance Treated?

Insulin resistance is traditionally treated by lifestyle modification, diet, and exercise. The Mediterranean diet is a good option for many people with PCOS. Metformin is often prescribed as a first-line treatment, but Ozempic can be an alternative for people who cannot tolerate metformin or if metformin is not working well.

How is Ozempic Taken?

Ozempic is taken as a weekly injection using a special pen that can be self-administered. There is an oral alternative, Rybelsus, that can be taken instead. Ozempic can be taken with or without food.

What are the Side Effects of Ozempic?

Common side effects of Ozempic include nausea, vomiting, diarrhea or constipation, and stomach ache. Rare side effects include injection site reactions, pancreatitis, complications for diabetics with a history of diabetic retinopathy, hypoglycemia, acute kidney injury, fatigue, dizziness, increased risk of gallstones, and increased risk of thyroid cancer.

The Lowdown

Metformin is a first-line treatment for most people with PCOS who are trying to get pregnant. Ozempic may be prescribed if metformin makes you sick or does not work, or it may be prescribed alongside metformin. Ozempic can help control insulin resistance and prevent it from developing into type 2 diabetes and can help with weight loss. For some patients with PCOS, Ozempic is a highly beneficial drug.